dose (mcg/kg/min) x weight (kg) x 60 min/hr. For repeated courses, the total For most patients, the choice between routes should be based on individual preference, and the regimen should be individualized to achieve the desired outcomes. The formula for the Drip Rate: Drip Rate = Volume (mL) Time (h). The dose used in the NIH trials was 2 grams/kg of child’s weight (1 gm/kg per day for 2 days). The Bloody Easy 4 and Bloody Easy Blood Administration flipbooks are viewable on any desktop PC, smartphone or tablet. The Dose Calculator is intended to be used when determining the dose of IVIG for clinically obese patients. Dose. The dose of Octagam 5% liquid for replacement therapy in primary humoral immunodeficiency diseases is 300 to 600 mg/kg body weight (6-12 mL/kg) administered every 3 to 4 weeks. App for iPhone. A total of 18.7% of clinic notes following IVIG had no mention of efficacy. For other patients, the dosing information recommended in the BC IVIG Utilization Management guidelines should be followed. If you want to calculate the dose of a medication, you need to use the following equation: dose = weight * dosage. patients receiving IVIG treatment, including GAMUNEX-C. IV Infusion Rate (cc/hr) =. NOTE: This only impacts our online program. Initiating Hizentra therapy for PI. The program allows to calculate the infusion rate of drugs. The TML shall check the dose using the NLPBCP IVIG dose calculator or facility equivalent. calculate the dosing weight as well as the resulting IVIG dose. DISCLAIMER: All calculations must be confirmed before use. 0.5 mg/kg/min (0.005 mL/kg/min) Increase to 8 mg/kg/min (0.08 mL/kg/min) Monitor the patient’s vital signs throughout the infusion. Please find alternative IVIG Dosing Calculators below: Alberta Health Services IVIG Dosing Calculator; British Columbia Provincial Health Services Authority IVIG Dosing Calculator Background:  An online calculator has been published on AHS external website (available at: https://www.albertahealthservices.ca/webapps/labservices/IVIG_Dosing_Calculator.htm) to calculate the dosing weight as well as the resulting IVIG dose. Note that it is acceptable to prescribe lower than the calculated dose. -Infuse at 0.5 mg/kg/min for the first 10 minutes of the infusion. Visit. Alternative IVIG Dosing Calculators. Obesity is a very common condition; however, the effect of excess body weight on the appropriate dose of immunoglobulin has not been defined empirically. If dosing methods 1, 2, and 3 had been used, the annual use of IVIG would have decreased by 21.9% (16,658 g/year, p < 0.001), 24.2% (18,371 g/year, p < 0.001), and 35.9% (27,252 g/year, p < 0.001), respectively. Adjust the dosage over time to achieve the desired trough levels and clinical responses. An ideal body weight calculator allowing for calculation of appropriately adjusted doses of IVIG for obese patients. Bloody Easy Lite. cutaquig® Dose Calculator Keep Going cutaquig® may be infused into multiple injection sites. Bottom line: Keeping with a meat analogy, the IVIG app is more like lean turkey than a fatty beef patty in a fast-food burger. You will find a med calculator for BMI, creatinine clearance, metric to english conversion and more. 3.  Authorized prescribers of intravenous immunoglobulin (IVIG) in Alberta will be required to prescribe using adjusted body weight dosing for patients. Immunoglobulin is not lipid soluble. Rates per gram are effective April 1, 2021, through June 30, 2021. This topic will review the uses, proposed mechanisms of action, and administration of intravenous immune globulin (IVIG). Patient's height and weight required. IVIG is commonly administered as part of a treatment protocol that includes plasmapheresis. The PBCO is pleased to provide the BMI (Body Mass Index) Calculator and the IVIG Dosing Calculator as mobile web applications for convenient access on the go. Carimune (R): 400 to 800 mg/kg, IV, every 3 to 4 weeks. Enter your data below in these fields (*) to calculate your reimbursement for Quarter 2, 2021. However, there is no scientific evidence that either is more beneficial. Initial weekly dose = Previous IVIG or HYQVIA dose (in grams) / Number of weeks between IVIG or HYQVIA doses * 1.30. (Note) **Review MOHLTC approved IVIG indications and doses (N A total of 9,918 doses were administered to 2,564 patients over 5 years, representing an average usage of 75,994 g/year. Intravenous Infusion Calculations Drip Rates — is when the infusion volume is calculated into drops. 12 This extended half-life has been used to calculate a dose infusion frequency for IVIG of ‘every 3 weeks’. The information provided on this site, including links to relevant websites and the information contained therein, is for use by health care providers and health care organizations only. in CIDP, and who tolerate IVIg well, doses up to 2.0 g/kg can be given continuously over 24 h or as two separate doses of 1.0 g/kg on consecutive days, thus avoiding the need for an overnight stay. Maximum infusion rate (if tolerated) 200–800 mg/kg (2–8 mL/kg) every 3–4 weeks. The ORBCoN app is a handy reference tool for IVIG guidelines and dose calculations that comes without pretensions and delivers on its promise. Patient's height and weight required. Version 3, January 31, 2018. Weight is the patients weight, expressed in kg or lb. Weekly: Start Hizentra 1 week after last Intravenous Immune Globulin (Human) (IVIg) infusion. Immunoglobulin therapy plays a critical role in the treatment of immunodeficiency disorders as well as autoimmune and inflammatory conditions. IVIG is used in conjunction with immunosuppressive medications and/or plasmapheresis. IV administration is suitable for a wide variety of CIDP patients. This entry was posted in Uncategorized. adults) under 5ft in height. We can confirm that there has been no security breach. For patients needing repeated courses, e.g. In terms of therapeutic effect, it is not known which IgG PK parameter helps define the best possible outcome (peak versus trough level, change in IgG level, steady-state level, etc. Calculator Blood Transfusion IVIg Request Form Surname Forename Ward Hospital No. Previous IVIg dose (in grams) No. Offline programs uploaded to hospital learning management systems are unaffected. (Note) **Review MOHLTC approved IVIG indications and doses (N **If "Reason for IVIG" is other, provide information in Comments. Dose: Initial dose: Total dose of 2 g/kg divided over 2 to 5 days in adults and children. -Maximum infusion rate is 6 mg/kg/min. Note that it is acceptable to prescribe lower than the calculated dose. 5. The supply of IVIg is limited and demand continues to exceed supply therefore a guideline was developed for a more evidence-based approach to IVIg use. 1 g/kg (10 mL/kg) daily for 2 consecutive days. Initial infusion rate. 0.5 mg/kg/min (0.005 mL/kg/min) Maximum infusion rate (if tolerated) Increase to 4 mg/kg/min (0.04 mL/kg/min) Dose. Initial infusion rate. Maximum infusion rate (if tolerated) 1 g/kg (10 mL/kg) daily for 2 consecutive days. Bivigam (R): 300 to 800 mg/kg, IV, every 3 to 4 weeks. EXCEPTION: use actual weight for Pediatric patients (age less than 18 years) and for patient's height less than 5 feet or 152.4 cm. For other patients, the dosing information recommended in the Newfoundland and Labrador Utilization of IVIG policy and standard operating procedure for review and approval of requests for IVIG in adults should be followed. It is very important that you input an accurate result. Keywords:dosing,immunoglobulin,IVIg,obesity,primaryimmunodeficiency Introduction It is recommended to dose immunoglobulin (Ig) for both replacement and autoimmune indications with reference to actual body weight [1,2]; however, clinicians have long queried … Definitely 'Good vibrations' (Beach Boys 1966 classic) You'll need to select the patient's weight, dilution of the solution. BMI Calculator Bookmark the permalink. Pooled analyses show that at equivalent total doses, weekly SCIG results in steady-state levels 10-20% higher than troughs on monthly IVIG. the dose any more quickly or more slowly would be detrimental. Slow or stop the infusion if adverse reactions occur. Regimens for administration include IVIG after each plasmapheresis treatment or as a set dose of 2 g/kg total, alone or if given with plasmapheresis after the final plasmapheresis treatment. of weeks between IVIg doses) X 1.37. The maximum amount of IVIG administered shall reflect adjusted body weight dosing in patients with a minimum height of 152.4 cm (60 inches) and/or a minimum weight of 45 kg. cutaquig® Dose Calculator The recommended weekly dose of cutaquig® is 0.1–0.2g per kg of body weight. Privigen does not contain sucrose. This should be administered subcutaneously. Neither the monographs nor the dose calculator is intended to replace sound clinical judgment concerning a patient's unique situation. Coordinating Network (ORBCoN) dose calculator. IVIG Dose Calculator. (IGIV) products in predisposed patients. The Plasma Protein Product (PPP) portion of the provincial redistribution program is a partnership between the Ontario Regional Blood Coordinating Network (ORBCoN) and the Factor Concentrate Redistribution Program (FCRP). Initial weekly dose = (Previous IVIg dose [in grams] / No. Our developers are aware and working towards a fix. Immune globulin derived from the plasma of paid donors is used in the treatment of an array of disorders, including primary and secondary immune deficiency states and a variety of autoimmune and inflammatory disorders. Maintenance dose may be considered depending on response to treatment. IVIG TREATMENT PROTOCOL. Usual Adult Dose for Primary Immunodeficiency Syndrome. Dose. IVIG patients shall be dosed through the adjusted body weight calculation. In immunodeficient patients, there has been controversy whether initial loading doses of intravenous (IVIG) should be based on actual body weight or a calculated parameter such as adjusted body weight in obese patients. You will find over 20 financial calculators related to retirement, savings, investments, mortgages, and loans. Note* IVIG Reimbursement Calculator has been updated with the latest Rates as per BSTQ Magazine Q2 2021. Dose Calculator. Bloody Easy Tech Assessment. Offline. BMI/Dose Calculator. For other patients, the dosing information recommended in the BC IVIG Utilization Management guidelines should be followed. Neither the guidelines nor the dose calculator is intended to replace sound clinical judgment concerning a patient's unique situation. Height must be between 153-241 cm (60-95 inches). 4. Example 1 A patient is ordered to receive 1000 mL of intravenous fluids to run over 8 hours. The indications are colour coded to ... • Calculate the dose using the actual body weight (kg). concentration (mg/cc) x 1000 mcg/mg. Related | Adult IVIG Infusion Rate Calculator (10 Percent Product Only) View Fullscreen. Equilibrium was achieved in 3–5 days. The high-dose regimen (1g/kg x 1-2 days) is not recommended for individuals with -If tolerated, may increase infusion rate by 0.8 mg/kg/min every 20 minutes. It is recommended that the initial infusion rate be used for the first 30 minutes. Dosage calculation formulas. Both comments and trackbacks are currently closed. Conclusion. (Use dose determining weight (DDW) if … We are currently experiencing outages. Dosage is the prescribed amount of drug in mg per kg of body weight. The authors make no claims of the accuracy of the information contained herein; and these suggested doses are not a substitute for clinical judgement. The proposed pharmacokinetic differences between lean and obese patients and the opportunity to reduce costs has led to the proposition that obese … ). Certain severe adverse drug … Initial infusion rate. Injection sites should be … There have been reports of aseptic meningitis, hemolytic anemia, and noncardiogenic pulmonary edema (transfusion-related acute lung injury [TRALI]) in patients administered with IVIG, including GAMUNEX-C. The Dose Calculator is intended to be used when determining the dose of IVIG for clinically obese patients; it is not recommended for pediatric patients nor any patients (incl. Based on calculated blood volumes, some have suggested that the dose could be reduced to 1.5gm/kg (750 mg/kg per day x 2 days). Our audit demonstrates a lack of compliance with IVIG Request Form requirements, a lack of documentation of diagnostic criteria and efficacy, and suggests inappropriate use of IVIG. This program is a professional medical calculator and intended for use only health care professionals. The goal is to provide the lowest possible dose that ... the authorized prescriber is responsible for calculating the adjusted dose, and providing this information on the Provincial IVIG request form at; Renal dysfunction and acute renal failure occur more commonly in patients receiving IGIV products that contain sucrose. UW Health Clinical Tool Terms. EXCEPTION: use actual weight for Pediatric patients (age less than 18 years) and for patient's height less than 5 feet or 152.4 cm. Read more. Bloody Easy Blood Administration and Bloody Easy 4 are Now Available in Flipbooks. The NSPBCP application is easy to use and ideal for physicians who want a quick reference to the IVIG dose calculator based on Adjusted Body Weight and Nova Scotia's Intravenous Immune Globulin (IVIG) Guidelines for the most common adult and pediatric indications. To add these web apps to your smart phone’s home screen, click on the applicable link below for easy-to-follow instructions: App for Android (OS 2.3) App for Blackberry. **Dose Calculation: utilize the Ontario Regional Blood Coordinating Network (ORBCoN) dose calculator. If well tolerated, the rate may be gradually increased to a maximum of 0.08 mL/kg per minute (8 mg/kg/min). Please note, to use this calculator: Height must be between 153-241 cm (60-95 inches). of weeks between IVIg doses. • For patients at risk of thrombosis, renal dysfunction or renal failure, administer Privigen at the minimum dose and infusion rate practicable. ORBCoN’s Resources for Clinicians. Establish the initial weekly dose by converting the monthly IVIG or HYQVIA dose into an equivalent weekly dose and increasing it using a dose adjustment factor (1.30). It is acceptable to give the smallest IVIG dose that provides clinical efficacy. Published: Now available, easy to use IVIG Dose Calculator.

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